Compensatory Increases in Nuclear PGC1α Protein Are Primarily Associated With Subsarcolemmal Mitochondrial Adaptations in ZDF Rats
OBJECTIVE: We examined in insulin-resistant muscle if, in contrast to long-standing dogma, mitochondrial fatty acid oxidation is increased and whether this is attributed to an increased nuclear content of peroxisome proliferator–activated receptor (PPAR) γ coactivator (PGC) 1α and the adaptations of...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844829/ https://www.ncbi.nlm.nih.gov/pubmed/20103701 http://dx.doi.org/10.2337/db09-1519 |