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Compensatory Increases in Nuclear PGC1α Protein Are Primarily Associated With Subsarcolemmal Mitochondrial Adaptations in ZDF Rats

OBJECTIVE: We examined in insulin-resistant muscle if, in contrast to long-standing dogma, mitochondrial fatty acid oxidation is increased and whether this is attributed to an increased nuclear content of peroxisome proliferator–activated receptor (PPAR) γ coactivator (PGC) 1α and the adaptations of...

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Detalles Bibliográficos
Autores principales:	Holloway, Graham P., Gurd, Brendon J., Snook, Laelie A., Lally, Jamie, Bonen, Arend
Formato:	Texto
Lenguaje:	English
Publicado:	American Diabetes Association 2010
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844829/ https://www.ncbi.nlm.nih.gov/pubmed/20103701 http://dx.doi.org/10.2337/db09-1519

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