Deficiency of Phosphoinositide 3-Kinase Enhancer Protects Mice From Diet-Induced Obesity and Insulin Resistance

OBJECTIVE: Phosphoinositide 3-kinase enhancer A (PIKE-A) is a proto-oncogene that promotes tumor growth and transformation by enhancing Akt activity. However, the physiological functions of PIKE-A in peripheral tissues are unknown. Here, we describe the effect of PIKE deletion in mice and explore th...

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Detalles Bibliográficos
Autores principales: Chan, Chi Bun, Liu, Xia, Jung, Dae Young, Jun, John Y., Luo, Hongbo R., Kim, Jason K., Ye, Keqiang
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844836/
https://www.ncbi.nlm.nih.gov/pubmed/20068140
http://dx.doi.org/10.2337/db09-1404

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844836/
https://www.ncbi.nlm.nih.gov/pubmed/20068140
http://dx.doi.org/10.2337/db09-1404

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