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CB1 Antagonism Exerts Specific Molecular Effects on Visceral and Subcutaneous Fat and Reverses Liver Steatosis in Diet-Induced Obese Mice

OBJECTIVE: The beneficial effects of the inactivation of endocannabinoid system (ECS) by administration of antagonists of the cannabinoid receptor (CB) 1 on several pathological features associated with obesity is well demonstrated, but the relative contribution of central versus peripheral mechanis...

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Detalles Bibliográficos
Autores principales: Jourdan, Tony, Djaouti, Louiza, Demizieux, Laurent, Gresti, Joseph, Vergès, Bruno, Degrace, Pascal
Formato: Texto
Lenguaje:English
Publicado: American Diabetes Association 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844840/
https://www.ncbi.nlm.nih.gov/pubmed/20110567
http://dx.doi.org/10.2337/db09-1482