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Cyclin D2 Is Essential for the Compensatory β-Cell Hyperplastic Response to Insulin Resistance in Rodents
OBJECTIVE: A major determinant of the progression from insulin resistance to the development of overt type 2 diabetes is a failure to mount an appropriate compensatory β-cell hyperplastic response to maintain normoglycemia. We undertook the present study to directly explore the significance of the c...
Autores principales: | Georgia, Senta, Hinault, Charlotte, Kawamori, Dan, Hu, Jiang, Meyer, John, Kanji, Murtaza, Bhushan, Anil, Kulkarni, Rohit N. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2844846/ https://www.ncbi.nlm.nih.gov/pubmed/20103709 http://dx.doi.org/10.2337/db09-0838 |
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