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A rapid, sensitive, reproducible and cost-effective method for mutation profiling of colon cancer and metastatic lymph nodes

BACKGROUND: An increasing number of studies show that genetic markers can aid in refining prognostic information and predicting the benefit from systemic therapy. Our goal was to develop a high throughput, cost-effective and simple methodology for the detection of clinically relevant hot spot mutati...

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Detalles Bibliográficos
Autores principales: Fumagalli, Debora, Gavin, Patrick G, Taniyama, Yusuke, Kim, Seung-Il, Choi, Hyun-Joo, Paik, Soonmyung, Pogue-Geile, Katherine L
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845115/
https://www.ncbi.nlm.nih.gov/pubmed/20233444
http://dx.doi.org/10.1186/1471-2407-10-101