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DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm

There is an increased prevalence of imprinting disorders, such as Beckwith–Wiedemann syndrome, associated with human assisted reproductive technologies (ART). Work on animal models suggests that in vitro culture may be the source of these imprinting errors. However, in this study we report that, in...

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Detalles Bibliográficos
Autores principales: Kobayashi, Hisato, Hiura, Hitoshi, John, Rosalind M, Sato, Akiko, Otsu, Eiko, Kobayashi, Naoko, Suzuki, Rei, Suzuki, Fumihiko, Hayashi, Chika, Utsunomiya, Takafumi, Yaegashi, Nobuo, Arima, Takahiro
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845511/
https://www.ncbi.nlm.nih.gov/pubmed/19471309
http://dx.doi.org/10.1038/ejhg.2009.68