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DNA methylation errors at imprinted loci after assisted conception originate in the parental sperm
There is an increased prevalence of imprinting disorders, such as Beckwith–Wiedemann syndrome, associated with human assisted reproductive technologies (ART). Work on animal models suggests that in vitro culture may be the source of these imprinting errors. However, in this study we report that, in...
Autores principales: | Kobayashi, Hisato, Hiura, Hitoshi, John, Rosalind M, Sato, Akiko, Otsu, Eiko, Kobayashi, Naoko, Suzuki, Rei, Suzuki, Fumihiko, Hayashi, Chika, Utsunomiya, Takafumi, Yaegashi, Nobuo, Arima, Takahiro |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845511/ https://www.ncbi.nlm.nih.gov/pubmed/19471309 http://dx.doi.org/10.1038/ejhg.2009.68 |
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