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Pancratistatin induces apoptosis in clinical leukemia samples with minimal effect on non-cancerous peripheral blood mononuclear cells

BACKGROUND: Pancratistatin, a natural compound extracted from Hymenocallis littoralis, can selectively induce apoptosis in several cancer cell lines. In this ex vivo study, we evaluated the effect of pancratistatin on peripheral blood mononuclear cells obtained from 15 leukemia patients prior to cli...

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Detalles Bibliográficos
Autores principales: Griffin, Carly, Hamm, Caroline, McNulty, James, Pandey, Siyaram
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845577/
https://www.ncbi.nlm.nih.gov/pubmed/20205924
http://dx.doi.org/10.1186/1475-2867-10-6