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HIV and Mature Dendritic Cells: Trojan Exosomes Riding the Trojan Horse?
Exosomes are secreted cellular vesicles that can induce specific CD4(+) T cell responses in vivo when they interact with competent antigen-presenting cells like mature dendritic cells (mDCs). The Trojan exosome hypothesis proposes that retroviruses can take advantage of the cell-encoded intercellula...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845607/ https://www.ncbi.nlm.nih.gov/pubmed/20360840 http://dx.doi.org/10.1371/journal.ppat.1000740 |