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HIV and Mature Dendritic Cells: Trojan Exosomes Riding the Trojan Horse?

Exosomes are secreted cellular vesicles that can induce specific CD4(+) T cell responses in vivo when they interact with competent antigen-presenting cells like mature dendritic cells (mDCs). The Trojan exosome hypothesis proposes that retroviruses can take advantage of the cell-encoded intercellula...

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Detalles Bibliográficos
Autores principales: Izquierdo-Useros, Nuria, Naranjo-Gómez, Mar, Erkizia, Itziar, Puertas, Maria Carmen, Borràs, Francesc E., Blanco, Julià, Martinez-Picado, Javier
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845607/
https://www.ncbi.nlm.nih.gov/pubmed/20360840
http://dx.doi.org/10.1371/journal.ppat.1000740