Cargando…

Isoform-Specific Regulation and Localization of the Coxsackie and Adenovirus Receptor in Human Airway Epithelia

Adenovirus is an important respiratory pathogen. Adenovirus fiber from most serotypes co-opts the Coxsackie-Adenovirus Receptor (CAR) to bind and enter cells. However, CAR is a cell adhesion molecule localized on the basolateral membrane of polarized epithelia. Separation from the lumen of the airwa...

Descripción completa

Detalles Bibliográficos
Autores principales: Excoffon, Katherine J. D. A., Gansemer, Nicholas D., Mobily, Matthew E., Karp, Philip H., Parekh, Kalpaj R., Zabner, Joseph
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845650/
https://www.ncbi.nlm.nih.gov/pubmed/20361046
http://dx.doi.org/10.1371/journal.pone.0009909