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Transgenic Rat Model of Neurodegeneration Caused by Mutation in the TDP Gene
TDP-43 proteinopathies have been observed in a wide range of neurodegenerative diseases. Mutations in the gene encoding TDP-43 (i.e., TDP) have been identified in amyotrophic lateral sclerosis (ALS) and in frontotemporal lobe degeneration associated with motor neuron disease. To study the consequenc...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845661/ https://www.ncbi.nlm.nih.gov/pubmed/20361056 http://dx.doi.org/10.1371/journal.pgen.1000887 |