Cargando…
Transgenic Rat Model of Neurodegeneration Caused by Mutation in the TDP Gene
TDP-43 proteinopathies have been observed in a wide range of neurodegenerative diseases. Mutations in the gene encoding TDP-43 (i.e., TDP) have been identified in amyotrophic lateral sclerosis (ALS) and in frontotemporal lobe degeneration associated with motor neuron disease. To study the consequenc...
Autores principales: | Zhou, Hongxia, Huang, Cao, Chen, Han, Wang, Dian, Landel, Carlisle P., Xia, Pedro Yuxing, Bowser, Robert, Liu, Yong-Jian, Xia, Xu Gang |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845661/ https://www.ncbi.nlm.nih.gov/pubmed/20361056 http://dx.doi.org/10.1371/journal.pgen.1000887 |
Ejemplares similares
-
Developing tTA Transgenic Rats for Inducible and Reversible Gene Expression
por: Zhou, Hongxia, et al.
Publicado: (2009) -
Sustained Expression of TDP-43 and FUS in Motor Neurons in Rodent's Lifetime
por: Huang, Cao, et al.
Publicado: (2010) -
TDP-43 Potentiates Alpha-synuclein Toxicity to Dopaminergic Neurons in Transgenic Mice
por: Tian, Tian, et al.
Publicado: (2011) -
FUS Transgenic Rats Develop the Phenotypes of Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration
por: Huang, Cao, et al.
Publicado: (2011) -
Does a loss of TDP-43 function cause neurodegeneration?
por: Xu, Zuo-Shang
Publicado: (2012)