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Ubc9 promotes breast cell invasion and metastasis in a sumoylation-independent manner

Ubc9 is an E2 conjugating enzyme that transfers the activated SUMO (small ubiquitin-related modifier) to protein substrates, and thus it plays a critical role in sumoylation-mediated cellular pathways. We have previously reported that Ubc9 promotes tumor growth in the xenograft mouse model using bre...

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Detalles Bibliográficos
Autores principales: Zhu, Shuomin, Sachdeva, Mohit, Wu, Fangting, Lu, Zhaohui, Mo, Yin-Yuan
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845735/
https://www.ncbi.nlm.nih.gov/pubmed/20023705
http://dx.doi.org/10.1038/onc.2009.459