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Ubc9 promotes breast cell invasion and metastasis in a sumoylation-independent manner
Ubc9 is an E2 conjugating enzyme that transfers the activated SUMO (small ubiquitin-related modifier) to protein substrates, and thus it plays a critical role in sumoylation-mediated cellular pathways. We have previously reported that Ubc9 promotes tumor growth in the xenograft mouse model using bre...
Autores principales: | , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845735/ https://www.ncbi.nlm.nih.gov/pubmed/20023705 http://dx.doi.org/10.1038/onc.2009.459 |