TGFβ mediated upregulation of hepatic miR-181b promotes hepatocarcinogenesis by targeting TIMP3

To identify microRNAs that may play a causal role in hepatocarcinogenesis, we used an animal model in which C57/BL6 mice fed choline deficient and amino acid defined (CDAA) diet develop preneoplastic lesions at 65 weeks and hepatocellular carcinomas after 84 weeks. miRNA expression profiling showed...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Hsu, Shu-Hao, Majumder, Sarmila, Kutay, Huban, Huang, Wei, Jacob, Samson T., Ghoshal, Kalpana
Formato: Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845743/
https://www.ncbi.nlm.nih.gov/pubmed/20023698
http://dx.doi.org/10.1038/onc.2009.468

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845743/
https://www.ncbi.nlm.nih.gov/pubmed/20023698
http://dx.doi.org/10.1038/onc.2009.468

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