Rapid Inactivation of Proteins by Rapamycin-Induced Rerouting to Mitochondria

We have developed a method for rapidly inactivating proteins with rapamycin-induced heterodimerization. Cells were stably transfected with siRNA-resistant, FKBP-tagged subunits of the adaptor protein (AP) complexes of clathrin-coated vesicles (CCVs), together with an FKBP and rapamycin-binding domai...

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Detalles Bibliográficos
Autores principales: Robinson, Margaret S., Sahlender, Daniela A., Foster, Samuel D.
Formato: Texto
Lenguaje:English
Publicado: Cell Press 2010
Materias:
Resource
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845799/
https://www.ncbi.nlm.nih.gov/pubmed/20159602
http://dx.doi.org/10.1016/j.devcel.2009.12.015

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845799/
https://www.ncbi.nlm.nih.gov/pubmed/20159602
http://dx.doi.org/10.1016/j.devcel.2009.12.015

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