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Signal strength and signal duration define two distinct aspects of JNK-regulated axon stability
Signaling proteins often control multiple aspects of cell morphogenesis. Yet the mechanisms that govern their pleiotropic behavior are often unclear. Here we show activity levels and timing mechanisms determine distinct aspects of Jun N-terminal kinase (JNK) pathway dependent axonal morphogenesis in...
Autores principales: | , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2845820/ https://www.ncbi.nlm.nih.gov/pubmed/20035736 http://dx.doi.org/10.1016/j.ydbio.2009.12.016 |