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Dapdiamides, Tripeptide Antibiotics Formed by Unconventional Amide Ligases†

[Image: see text] Construction of a genomic DNA library from Pantoea agglomerans strain CU0119 and screening against the plant pathogen Erwinia amylovora yielded a new family of antibiotics, dapdiamides A−E (1−5). The structures were established through 2D-NMR experiments and mass spectrometry, as w...

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Detalles Bibliográficos
Autores principales: Dawlaty, Jessica, Zhang, Xiaorong, Fischbach, Michael A., Clardy, Jon
Formato: Texto
Lenguaje:English
Publicado: American Chemical Society and American Society of Pharmacognosy 2009
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846032/
https://www.ncbi.nlm.nih.gov/pubmed/20041689
http://dx.doi.org/10.1021/np900685z