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Proteomics Strategy for Identifying Candidate Bioactive Proteins in Complex Mixtures: Application to the Platelet Releasate

Proteomic approaches have proven powerful at identifying large numbers of proteins, but there are fewer reports of functional characterization of proteins in biological tissues. Here, we describe an experimental approach that fractionates proteins released from human platelets, linking bioassay acti...

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Detalles Bibliográficos
Autores principales: O'Connor, Roisin, Cryan, Lorna M., Wynne, Kieran, de Stefani, Andreas, Fitzgerald, Desmond, O'Brien, Colm, Cagney, Gerard
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846341/
https://www.ncbi.nlm.nih.gov/pubmed/20368775
http://dx.doi.org/10.1155/2010/107859