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Glutathione-S-transferase genes and asthma phenotypes: a Human Genome Epidemiology (HuGE) systematic review and meta-analysis including unpublished data

Background Oxidative stress is thought to be involved in the pathogenesis of asthma. Glutathione-S-transferase (GST) enzymes, which play an important role in antioxidant defences, may therefore influence asthma risk. Two common deletion polymorphisms of GSTM1 and GSTT1 genes and the GSTP1 Ile105Val...

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Detalles Bibliográficos
Autores principales: Minelli, Cosetta, Granell, Raquel, Newson, Roger, Rose-Zerilli, Matthew J, Torrent, Maties, Ring, Sue M, Holloway, John W, Shaheen, Seif O, Henderson, John A
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846443/
https://www.ncbi.nlm.nih.gov/pubmed/20032267
http://dx.doi.org/10.1093/ije/dyp337