Synthesis and Antimicrobial Evaluation of 5-Iodopyrimidine Analogs

4-Substituted-5-iodo-2-benzylthiopyrimidines were prepared efficiently in three steps. 2-Benzylthiopyrimidine on iodination in presence of base gave 5-iodo-2-benzylthiopyrimidine (1), which on chlorination with excess of POCl(3) furnished 4-chloro-5-iodo-2-benzylthiopyrimidine (2). Reaction of 2 wit...

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Detalles Bibliográficos
Autores principales: Goudgaon, N. M., Basha, N. J., Patil, S. B.
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846474/
https://www.ncbi.nlm.nih.gov/pubmed/20376222
http://dx.doi.org/10.4103/0250-474X.59551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846474/
https://www.ncbi.nlm.nih.gov/pubmed/20376222
http://dx.doi.org/10.4103/0250-474X.59551

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