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Angiotensin II type 2 receptor signaling significantly attenuates growth of murine pancreatic carcinoma grafts in syngeneic mice

BACKGROUND: Pancreatic cancer is one of the most aggressive human malignancies, with a very poor prognosis. To evaluate the effect of angiotensin II (Ang II) type 2 receptor (AT(2)) expression in the host's body on the growth of pancreatic carcinoma, we have investigated the growth of mouse pan...

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Detalles Bibliográficos
Autores principales: Doi, Chiyo, Egashira, Noboru, Kawabata, Atsushi, Maurya, Dharmendra Kumar, Ohta, Naomi, Uppalapati, Deepthi, Ayuzawa, Rie, Pickel, Lara, Isayama, Yuka, Troyer, Deryl, Takekoshi, Susumu, Tamura, Masaaki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846883/
https://www.ncbi.nlm.nih.gov/pubmed/20181281
http://dx.doi.org/10.1186/1471-2407-10-67