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RHOA and PRKCZ control different aspects of cell motility in pancreatic cancer metastatic clones

BACKGROUND: Our understanding of the mechanism regulating pancreatic cancer metastatic phenotype is limited. We analyzed the role of RHOA and PRKCZ in the motility attitude of two subclones of the pancreatic adenocarcinoma cell line SUIT-2 (S2), with different in vivo metastatic potential in nude mi...

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Detalles Bibliográficos
Autores principales: Peruta, Marco Della, Giagulli, Cinzia, Laudanna, Carlo, Scarpa, Aldo, Sorio, Claudio
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846889/
https://www.ncbi.nlm.nih.gov/pubmed/20236512
http://dx.doi.org/10.1186/1476-4598-9-61