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Nrf2 protects against pulmonary fibrosis by regulating the lung oxidant level and Th1/Th2 balance

BACKGROUND: Pulmonary fibrosis is a progressive and lethal disorder. Although the precise mechanisms of pulmonary fibrosis are not fully understood, oxidant/antioxidant and Th1/Th2 balances may play an important role in many of the processes of inflammation and fibrosis. The transcription factor Nrf...

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Detalles Bibliográficos
Autores principales: Kikuchi, Norihiro, Ishii, Yukio, Morishima, Yuko, Yageta, Yuichi, Haraguchi, Norihiro, Itoh, Ken, Yamamoto, Masayuki, Hizawa, Nobuyuki
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846897/
https://www.ncbi.nlm.nih.gov/pubmed/20298567
http://dx.doi.org/10.1186/1465-9921-11-31