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Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes

BACKGROUND: Chaperonin proteins are well known for the critical role they play in protein folding and in disease. However, the recent identification of three diverged chaperonin paralogs associated with the human Bardet-Biedl and McKusick-Kaufman Syndromes (BBS and MKKS, respectively) indicates that...

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Detalles Bibliográficos
Autores principales: Mukherjee, Krishanu, Conway de Macario, Everly, Macario, Alberto JL, Brocchieri, Luciano
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846930/
https://www.ncbi.nlm.nih.gov/pubmed/20193073
http://dx.doi.org/10.1186/1471-2148-10-64