Variables with time-varying effects and the Cox model: Some statistical concepts illustrated with a prognostic factor study in breast cancer

BACKGROUND: The Cox model relies on the proportional hazards (PH) assumption, implying that the factors investigated have a constant impact on the hazard - or risk - over time. We emphasize the importance of this assumption and the misleading conclusions that can be inferred if it is violated; this...

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Detalles Bibliográficos
Autores principales: Bellera, Carine A, MacGrogan, Gaëtan, Debled, Marc, de Lara, Christine Tunon, Brouste, Véronique, Mathoulin-Pélissier, Simone
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846954/
https://www.ncbi.nlm.nih.gov/pubmed/20233435
http://dx.doi.org/10.1186/1471-2288-10-20

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2846954/
https://www.ncbi.nlm.nih.gov/pubmed/20233435
http://dx.doi.org/10.1186/1471-2288-10-20

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