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APP transgenic modeling of Alzheimer’s disease: mechanisms of neurodegeneration and aberrant neurogenesis

Neurodegenerative disorders of the aging population affect over 5 million people in the US and Europe alone. The common feature is the progressive accumulation of misfolded proteins with the formation of toxic oligomers. Alzheimer’s disease (AD) is characterized by cognitive impairment, progressive...

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Detalles Bibliográficos
Autores principales: Crews, Leslie, Rockenstein, Edward, Masliah, Eliezer
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847155/
https://www.ncbi.nlm.nih.gov/pubmed/20091183
http://dx.doi.org/10.1007/s00429-009-0232-6