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Riboswitch structure: an internal residue mimicking the purine ligand

The adenine and guanine riboswitches regulate gene expression in response to their purine ligand. X-ray structures of the aptamer moiety of these riboswitches are characterized by a compact fold in which the ligand forms a Watson–Crick base pair with residue 65. Phylogenetic analyses revealed a stri...

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Detalles Bibliográficos
Autores principales: Delfosse, Vanessa, Bouchard, Patricia, Bonneau, Eric, Dagenais, Pierre, Lemay, Jean-François, Lafontaine, Daniel A., Legault, Pascale
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847212/
https://www.ncbi.nlm.nih.gov/pubmed/20022916
http://dx.doi.org/10.1093/nar/gkp1080