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Riboswitch structure: an internal residue mimicking the purine ligand
The adenine and guanine riboswitches regulate gene expression in response to their purine ligand. X-ray structures of the aptamer moiety of these riboswitches are characterized by a compact fold in which the ligand forms a Watson–Crick base pair with residue 65. Phylogenetic analyses revealed a stri...
Autores principales: | Delfosse, Vanessa, Bouchard, Patricia, Bonneau, Eric, Dagenais, Pierre, Lemay, Jean-François, Lafontaine, Daniel A., Legault, Pascale |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847212/ https://www.ncbi.nlm.nih.gov/pubmed/20022916 http://dx.doi.org/10.1093/nar/gkp1080 |
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