Differential binding of Escherichia coli McrA protein to DNA sequences that contain the dinucleotide m5CpG

The Escherichia coli McrA protein, a putative C(5)-methylcytosine/C(5)-hydroxyl methylcytosine-specific nuclease, binds DNA with symmetrically methylated HpaII sequences (Cm5CGG), but its precise recognition sequence remains undefined. To determine McrA’s binding specificity, we cloned and expressed...

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Detalles Bibliográficos
Autores principales: Mulligan, Elizabeth A., Hatchwell, Eli, McCorkle, Sean R., Dunn, John J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Nucleic Acid Enzymes
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847215/
https://www.ncbi.nlm.nih.gov/pubmed/20015968
http://dx.doi.org/10.1093/nar/gkp1120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847215/
https://www.ncbi.nlm.nih.gov/pubmed/20015968
http://dx.doi.org/10.1093/nar/gkp1120

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