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Differential binding of Escherichia coli McrA protein to DNA sequences that contain the dinucleotide m5CpG
The Escherichia coli McrA protein, a putative C(5)-methylcytosine/C(5)-hydroxyl methylcytosine-specific nuclease, binds DNA with symmetrically methylated HpaII sequences (Cm5CGG), but its precise recognition sequence remains undefined. To determine McrA’s binding specificity, we cloned and expressed...
Autores principales: | Mulligan, Elizabeth A., Hatchwell, Eli, McCorkle, Sean R., Dunn, John J. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847215/ https://www.ncbi.nlm.nih.gov/pubmed/20015968 http://dx.doi.org/10.1093/nar/gkp1120 |
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