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Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency

Aptamers that can be regulated with light allow precise control of protein activity in space and time and hence of biological function in general. In a previous study, we showed that the activity of the thrombin-binding aptamer HD1 can be turned off by irradiation using a light activatable ‘caged’ i...

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Detalles Bibliográficos
Autores principales: Buff, Maximilian C. R., Schäfer, Florian, Wulffen, Bernhard, Müller, Jens, Pötzsch, Bernd, Heckel, Alexander, Mayer, Günter
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847219/
https://www.ncbi.nlm.nih.gov/pubmed/20007153
http://dx.doi.org/10.1093/nar/gkp1148