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Dependence of aptamer activity on opposed terminal extensions: improvement of light-regulation efficiency
Aptamers that can be regulated with light allow precise control of protein activity in space and time and hence of biological function in general. In a previous study, we showed that the activity of the thrombin-binding aptamer HD1 can be turned off by irradiation using a light activatable ‘caged’ i...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847219/ https://www.ncbi.nlm.nih.gov/pubmed/20007153 http://dx.doi.org/10.1093/nar/gkp1148 |