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Generation and bioenergetic analysis of cybrids containing mitochondrial DNA from mouse skeletal muscle during aging

Mitochondrial respiratory chain defects have been associated with various diseases and normal aging, particularly in tissues with high energy demands including skeletal muscle. Muscle-specific mitochondrial DNA (mtDNA) mutations have also been reported to accumulate with aging. Our understanding of...

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Detalles Bibliográficos
Autores principales: Li, Youfen, Li, Hong-Zhi, Hu, Peiqing, Deng, Janice, Banoei, Mohammad Mehdi, Sharma, Lokendra Kumar, Bai, Yidong
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847227/
https://www.ncbi.nlm.nih.gov/pubmed/20022917
http://dx.doi.org/10.1093/nar/gkp1162