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Generation and bioenergetic analysis of cybrids containing mitochondrial DNA from mouse skeletal muscle during aging
Mitochondrial respiratory chain defects have been associated with various diseases and normal aging, particularly in tissues with high energy demands including skeletal muscle. Muscle-specific mitochondrial DNA (mtDNA) mutations have also been reported to accumulate with aging. Our understanding of...
| Autores principales: | , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847227/ https://www.ncbi.nlm.nih.gov/pubmed/20022917 http://dx.doi.org/10.1093/nar/gkp1162 |