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Finding regulatory DNA motifs using alignment-free evolutionary conservation information

As an increasing number of eukaryotic genomes are being sequenced, comparative studies aimed at detecting regulatory elements in intergenic sequences are becoming more prevalent. Most comparative methods for transcription factor (TF) binding site discovery make use of global or local alignments of o...

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Detalles Bibliográficos
Autores principales: Gordân, Raluca, Narlikar, Leelavati, Hartemink, Alexander J.
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847231/
https://www.ncbi.nlm.nih.gov/pubmed/20047961
http://dx.doi.org/10.1093/nar/gkp1166