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Epstein–Barr Virus DNase (BGLF5) induces genomic instability in human epithelial cells

Epstein–Barr Virus (EBV) DNase (BGLF5) is an alkaline nuclease and has been suggested to be important in the viral life cycle. However, its effect on host cells remains unknown. Serological and histopathological studies implied that EBV DNase seems to be correlated with carcinogenesis. Therefore, we...

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Detalles Bibliográficos
Autores principales: Wu, Chung-Chun, Liu, Ming-Tsan, Chang, Yu-Ting, Fang, Chih-Yeu, Chou, Sheng-Ping, Liao, Hsin-Wei, Kuo, Kuan-Lin, Hsu, Shih-Lung, Chen, Yi-Ren, Wang, Pei-Wen, Chen, Yu-Lian, Chuang, Hsin-Ying, Lee, Chia-Huei, Chen, Ming, Wayne Chang, Wun-Shaing, Chen, Jen-Yang
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847232/
https://www.ncbi.nlm.nih.gov/pubmed/20034954
http://dx.doi.org/10.1093/nar/gkp1169