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Conformational changes in receptor tyrosine kinase signaling: an ErbB garden of delights

The ErbB family of receptor tyrosine kinases plays important roles in cell proliferation, differentiation, and apoptosis. Recent structural studies of these receptors have demonstrated dramatic conformational effects that are critical to their ligand binding and activation, and have shown that these...

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Detalles Bibliográficos
Autores principales: Carraway, Kermit L, Kozloski, Goldi A
Formato: Texto
Lenguaje:English
Publicado: Biology Reports Ltd 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847299/
https://www.ncbi.nlm.nih.gov/pubmed/20357902
http://dx.doi.org/10.3410/B1-72