Indole-3-Carbinol Triggers Aryl Hydrocarbon Receptor-dependent Estrogen Receptor (ER)α Protein Degradation in Breast Cancer Cells Disrupting an ERα-GATA3 Transcriptional Cross-Regulatory Loop

Estrogen receptor (ER)α is a critical target of therapeutic strategies to control the proliferation of hormone-dependent breast cancers. Preferred clinical options have significant adverse side effects that can lead to treatment resistance due to the persistence of active estrogen receptors. We have...

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Detalles Bibliográficos
Autores principales: Marconett, Crystal N., Sundar, Shyam N., Poindexter, Kevin M., Stueve, Theresa R., Bjeldanes, Leonard F., Firestone, Gary L.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847521/
https://www.ncbi.nlm.nih.gov/pubmed/20130088
http://dx.doi.org/10.1091/mbc.E09-08-0689

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847521/
https://www.ncbi.nlm.nih.gov/pubmed/20130088
http://dx.doi.org/10.1091/mbc.E09-08-0689

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