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PICH and Cotargeted Plk1 Coordinately Maintain Prometaphase Chromosome Arm Architecture

To maintain genomic stability, chromosome architecture needs to be tightly regulated as chromosomes undergo condensation during prophase and separation during anaphase, but the mechanisms remain poorly understood. Here, we show that the Plk1-binding protein PICH and Plk1 kinase coordinately maintain...

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Detalles Bibliográficos
Autores principales: Kurasawa, Yasuhiro, Yu-Lee, Li-yuan
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847523/
https://www.ncbi.nlm.nih.gov/pubmed/20130082
http://dx.doi.org/10.1091/mbc.E09-11-0950