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PICH and Cotargeted Plk1 Coordinately Maintain Prometaphase Chromosome Arm Architecture
To maintain genomic stability, chromosome architecture needs to be tightly regulated as chromosomes undergo condensation during prophase and separation during anaphase, but the mechanisms remain poorly understood. Here, we show that the Plk1-binding protein PICH and Plk1 kinase coordinately maintain...
Autores principales: | , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2010
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847523/ https://www.ncbi.nlm.nih.gov/pubmed/20130082 http://dx.doi.org/10.1091/mbc.E09-11-0950 |