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The Na(+)/H(+) Exchanger NHE6 in the Endosomal Recycling System Is Involved in the Development of Apical Bile Canalicular Surface Domains in HepG2 Cells

Polarized epithelial cells develop and maintain distinct apical and basolateral surface domains despite a continuous flux of membranes between these domains. The Na(+)/H(+)exchanger NHE6 localizes to endosomes but its function is unknown. Here, we demonstrate that polarized hepatoma HepG2 cells expr...

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Detalles Bibliográficos
Autores principales: Ohgaki, Ryuichi, Matsushita, Masafumi, Kanazawa, Hiroshi, Ogihara, Satoshi, Hoekstra, Dick, van IJzendoorn, Sven C.D.
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847532/
https://www.ncbi.nlm.nih.gov/pubmed/20130086
http://dx.doi.org/10.1091/mbc.E09-09-0767