The Ero1α-PDI Redox Cycle Regulates Retro-Translocation of Cholera Toxin

Cholera toxin (CT) is transported from the plasma membrane of host cells to the endoplasmic reticulum (ER) where the catalytic CTA1 subunit retro-translocates to the cytosol to induce toxicity. Our previous analyses demonstrated that the ER oxidoreductase protein disulfide isomerase (PDI) acts as a...

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Detalles Bibliográficos
Autores principales: Moore, Paul, Bernardi, Kaleena M., Tsai, Billy
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2010
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847533/
https://www.ncbi.nlm.nih.gov/pubmed/20130085
http://dx.doi.org/10.1091/mbc.E09-09-0826

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847533/
https://www.ncbi.nlm.nih.gov/pubmed/20130085
http://dx.doi.org/10.1091/mbc.E09-09-0826

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