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Mutagenesis analysis of the zinc-finger antiviral protein

BACKGROUND: The zinc-finger antiviral protein (ZAP) specifically inhibits the replication of certain viruses, including murine leukemia virus (MLV), by preventing the accumulation of viral mRNA in the cytoplasm. ZAP directly binds to the viral mRNA through the zinc-finger motifs and recruits the RNA...

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Detalles Bibliográficos
Autores principales: Wang, Xinlu, Lv, Fengxiang, Gao, Guangxia
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847535/
https://www.ncbi.nlm.nih.gov/pubmed/20226086
http://dx.doi.org/10.1186/1742-4690-7-19