Use of Human Cancer Cell Lines Mitochondria to Explore the Mechanisms of BH3 Peptides and ABT-737-Induced Mitochondrial Membrane Permeabilization

Current limitations of chemotherapy include toxicity on healthy tissues and multidrug resistance of malignant cells. A number of recent anti-cancer strategies aim at targeting the mitochondrial apoptotic machinery to induce tumor cell death. In this study, we set up protocols to purify functional mi...

Descripción completa

Detalles Bibliográficos
Autores principales: Buron, Nelly, Porceddu, Mathieu, Brabant, Magali, Desgué, Diana, Racoeur, Cindy, Lassalle, Myriam, Péchoux, Christine, Rustin, Pierre, Jacotot, Etienne, Borgne-Sanchez, Annie
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847598/
https://www.ncbi.nlm.nih.gov/pubmed/20360986
http://dx.doi.org/10.1371/journal.pone.0009924

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847598/
https://www.ncbi.nlm.nih.gov/pubmed/20360986
http://dx.doi.org/10.1371/journal.pone.0009924

Ejemplares similares