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Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes

BACKGROUND: Skeletal muscle insulin resistance (IR) is considered a critical component of type II diabetes, yet to date IR has evaded characterization at the global gene expression level in humans. MicroRNAs (miRNAs) are considered fine-scale rheostats of protein-coding gene product abundance. The r...

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Detalles Bibliográficos
Autores principales: Gallagher, Iain J, Scheele, Camilla, Keller, Pernille, Nielsen, Anders R, Remenyi, Judit, Fischer, Christian P, Roder, Karim, Babraj, John, Wahlestedt, Claes, Hutvagner, Gyorgy, Pedersen, Bente K, Timmons, James A
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847700/
https://www.ncbi.nlm.nih.gov/pubmed/20353613
http://dx.doi.org/10.1186/gm130