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TNFα Induces Choroid Plexus Epithelial Cell Barrier Alterations by Apoptotic and Nonapoptotic Mechanisms

The choroid plexus epithelium constitutes the structural basis of the blood-cerebrospinal fluid barrier. Since the cytokine TNFα is markedly increased during inflammatory diseases in the blood and the central nervous system, we investigated by which mechanisms TNFα induces barrier alteration in porc...

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Detalles Bibliográficos
Autores principales: Schwerk, Christian, Rybarczyk, Kasia, Essmann, Frank, Seibt, Annette, Mölleken, Marie-Louise, Zeni, Patrick, Schroten, Horst, Tenenbaum, Tobias
Formato: Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847764/
https://www.ncbi.nlm.nih.gov/pubmed/20369072
http://dx.doi.org/10.1155/2010/307231