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Energetics of gating at the apo–acetylcholine receptor transmitter binding site
Acetylcholine receptor channels switch between conformations that have a low versus high affinity for the transmitter and conductance for ions (R↔R*; gating). The forward isomerization, which begins at the transmitter binding sites and propagates ∼50 Å to the narrow region of the pore, occurs by app...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
The Rockefeller University Press
2010
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847916/ https://www.ncbi.nlm.nih.gov/pubmed/20351060 http://dx.doi.org/10.1085/jgp.200910384 |