An Accessory to the ‘Trinity’: SR-As Are Essential Pathogen Sensors of Extracellular dsRNA, Mediating Entry and Leading to Subsequent Type I IFN Responses

Extracellular RNA is becoming increasingly recognized as a signaling molecule. Virally derived double stranded (ds)RNA released into the extracellular space during virus induced cell lysis acts as a powerful inducer of classical type I interferon (IFN) responses; however, the receptor that mediates...

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Detalles Bibliográficos
Autores principales: DeWitte-Orr, Stephanie J., Collins, Susan E., Bauer, Carla M. T., Bowdish, Dawn M., Mossman, Karen L.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847946/
https://www.ncbi.nlm.nih.gov/pubmed/20360967
http://dx.doi.org/10.1371/journal.ppat.1000829

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2847946/
https://www.ncbi.nlm.nih.gov/pubmed/20360967
http://dx.doi.org/10.1371/journal.ppat.1000829

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