Functional Glycosylation of Dystroglycan Is Crucial for Thymocyte Development in the Mouse

BACKGROUND: Alpha-dystroglycan (α-DG) is a cell surface receptor providing a molecular link between the extracellular matrix (ECM) and the actin-based cytoskeleton. During its biosynthesis, α-DG undergoes specific and unusual O-glycosylation crucial for its function as a high-affinity cellular recep...

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Detalles Bibliográficos
Autores principales: Liou, Li-Ying, Walsh, Kevin B., Vartanian, Arineh R., Beltran-Valero de Bernabe, Daniel, Welch, Megan, Campbell, Kevin P., Oldstone, Michael B. A., Kunz, Stefan
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848029/
https://www.ncbi.nlm.nih.gov/pubmed/20369005
http://dx.doi.org/10.1371/journal.pone.0009915

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848029/
https://www.ncbi.nlm.nih.gov/pubmed/20369005
http://dx.doi.org/10.1371/journal.pone.0009915

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