Cargando…
Stoichiometry and intracellular fate of TRIM-containing TCR complexes
BACKGROUND: Studying the stoichiometry and intracellular trafficking of the T cell antigen receptor (TCR) is pivotal in understanding its mechanisms of activation. The αβTCR includes the antigen-binding TCRαβ heterodimer as well as the signal transducing CD3εγ, CD3εδ and ζ(2 )subunits. Although the...
Autores principales: | , , , , , , , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848047/ https://www.ncbi.nlm.nih.gov/pubmed/20298603 http://dx.doi.org/10.1186/1478-811X-8-5 |