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Inferring genetic interactions via a nonlinear model and an optimization algorithm

BACKGROUND: Biochemical pathways are gradually becoming recognized as central to complex human diseases and recently genetic/transcriptional interactions have been shown to be able to predict partial pathways. With the abundant information made available by microarray gene expression data (MGED), no...

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Detalles Bibliográficos
Autores principales: Chen, Chung-Ming, Lee, Chih, Chuang, Cheng-Long, Wang, Chia-Chang, Shieh, Grace S
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848194/
https://www.ncbi.nlm.nih.gov/pubmed/20184777
http://dx.doi.org/10.1186/1752-0509-4-16